Juq-565

The convergent two‑step synthesis afforded JUQ‑565 in an overall 80 % yield from commercially available starting materials. The key C‑N bond formation proceeded cleanly under mild conditions, enabling rapid analog generation for SAR studies. The final product displayed a calculated LogP of 3.1, consistent with favorable oral absorption.

“Old Harbor, berth nine,” Mara said. She let the ship take the route, not the fastest but the one with fewer eyes. JUQ-565

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