Right-click setup.exe > Properties > Compatibility tab. Select OS: Set it to "Windows XP (Service Pack 3)". Privileges: Check "Run this program as an administrator."
Attempting to run the AutoCAD 2000 setup.exe directly on Windows 10 64-bit will almost always result in a cryptic error: "This app can't run on your PC" or a silent failure. However, with a combination of compatibility settings, virtual machines, or specialized wrapper tools, installation is still possible. How To Install Autocad 2000 On Windows 10 64 Bit
Stable, functional, but requires launching a VM each time. Right-click setup
