Ensure the game has finished its "saving" routine before turning off the console. Some firmware versions require you to press Reset on the console to flush the save data to the SD card before powering down.
The ED64 Plus exists in a gray area:
Corrupted or outdated firmware is the #1 cause of the ED64 Plus failing to boot. How to Install or Update ED64 Plus Firmware ed64 plus firmware
While Alt64 adds "special case" game support, it may have minor bugs with some standard retail games that the stock firmware handles better. Ensure the game has finished its "saving" routine
Report compiled based on community documentation, reverse-engineering efforts, and user reports from 2015–2025. How to Install or Update ED64 Plus Firmware
: Specific firmware patches have been developed to enable the ED64 Plus to work with modern clones like the Analogue 3D . Common Issues & Troubleshooting
– your SD card is incompatible or not FAT32.