Clsi Document M45 Pdf Jun 2026

Standardizing AST for these rare bugs is a growing challenge. Studies show that using "non-standardized" methods (anything not specified in M45) can lead to inconsistent results, which is a major hurdle in combating antimicrobial resistance .

: Provides testing conditions and interpretive criteria for organisms like Corynebacterium spp., Abiotrophia spp., Granulicatella spp., and Bacillus spp. (excluding B. anthracis ). clsi document m45 pdf

The document describes traditional broth microdilution and agar disk diffusion methods, including standardized procedures for performance, drug selection, and quality control (QC). Standardizing AST for these rare bugs is a growing challenge